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ANIMAL HEALTH MONITORING SERVICES

(contract last updated 08/16/2013)

SCOPE: Contract for the purchase of Animal Health and Cell line Monitoring Services.

This contract will be used to assure animal health and cell line integrity and to monitor disease outbreaks and morbidity on this campus and its affiliated units. It is intended that all of Lot 1 will be awarded to one “Primary” Contractor with a possible “Secondary” Contractor also awarded. Lots 2 and 3 will be awarded based on responses received and the ability of the Contractors to provide the services being requested. The UW Madison Research Animal Resource Center (RARC) will use the contract for services for all UW-Madison animal care and affiliated units.

The UW requires the services of an animal serology and molecular diagnostics laboratory that will provide a cost effective and technologically superior means of ensuring animal health monitoring on the UW Madison campus (and affiliated units) as well as provide cell line diagnostics and educational and consultative services to the veterinary staff and investigators. We require such a program to be both cohesive and adaptable to the needs of the individual colleges providing comprehensive testing for serology/PCR, parasitology and specific research pursuits. Email notifications should be sent out for all tests submitted with positive results noted or highlighted for faster response. Reliably validated state of the art testing technologies should be used (to highest industry standards) and panels/profiles be able to be customized for the campus’s needs.

There must be an easy to use, flexible yet secure and well-supported web based database accessible from all parts of the campus (with password) that can accept submissions from multiple locations (yet still consider the whole of the campus submissions over time as regards pricing). This system should be configurable so that the University in conjunction with the Contractor can designate which logins at the University can view specific categories of reports, import and export data. Diagnostic health reports and health summary reports should easily fit on an 8.5x11 page and be easily understood and be able to be printed as a PDF. These reports should also be viewable in an online secure database format. Other needs include: ease of creating reports from serology and other testing data for use and export to templates such as transfer forms, the ability to track individual animals through room, building and investigator changes, the ability to search a wide range of parameters and the ability to upload in-house testing data (pathology, bacteriology and parasitology, etc.) and submitted by the UW and its affiliated units. Within a relatively short period of time (~3 months) all previous historical data from this campus’s databases and other companies should be incorporated into the chosen database. Data base assistance during work hours (7:00 AM – 5:00 PM, M-F, CST/CDT) should be available by phone and email and the database should be able to be further customized as needs require.

Educational materials and opportunities should be made available to the RARC staff and UW-Madison investigators with consultative services available by phone and email during working hours (7 am-5pm M-F CST) and emergency assistance available by phone if available. The Contractor should be actively engaged in research into new techniques for testing and threats to laboratory animal and cell line health and integrity and willing to collaborate with the contractor on emerging diseases and problems within the contractor’s animals and tissues.

The University has significant time invested in staff persons currently involved in the use of the current serology providers (500 hrs. + each). Proposers should identify how their services will be easily transferable between current users of competitors reports and methods.

CONTRACT #

DESCRIPTION

13-5462

ANIMAL HEALTH MONITORING SERVICES

CONTRACT ORIGIN:

ADDITIONAL INFORMATION:

UW-Madison
Purchasing Services
21 N Park St, Ste 6101
Madison, WI 53715-1218

UW-Madison users contact:
Vint Quamme
(608) 262-1147 FAX (608) 262-4467
vquamme@bussvc.wisc.edu

Non-UW-Madison users contact: Vendor Representative

COOPERATIVE PURCHASING:

YES

CONTRACT TERM:

August 1, 2013 through July 31, 2016, with automatic renewal extensions to July 31, 2018, unless amended, cancelled or rebid.

Vendor(s)

137530
Idexx Reference Laboratories Inc
4011 Discovery Dr
Columbia MO 65201

Sales Representative:	PHONE #	FAX #
James Grossman	847-212-4022	207-556-3749
E-mail james_grossman@idexx.com
	PHONE #	FAX #
Ordering/Expediting:	573-499-5726	573-499-5701
Invoice Information:	573-499-5722	573-499-5701
Returns:	573-499-5722	573-499-5701
Supplier Diversity Reporting:	573-499-5727	573-499-5701
Website: www.idexxradil.com

Commodity Code

962-06

Federal Employee ID # (FEIN)

01-0505450

F.O.B.

“D” F.O.B. DESTINATION, FREIGHT PREPAID AND ALLOWED

“V” F.O.B. SERVICE/MAINTENANCE

Terms:

N/30

Invoicing:

Invoices shall reflect contract pricing.

Other:

Pricing not available to: Other CIC member institutions

Pricing Information:

SEE BELOW RATE SCHEDULE

ITEM	DESCRIPTION	COST EACH SAMPLE/ASSAY
	Bid Component 1
1	Mouse parvo panel	$6.00
2	Mouse Level 3 Panel	$12.00
3	Mouse Custom Prevalent	$18.00
4	Mouse Custom Comprehensive	$36.00
5	Rat parvo panel	$12.00
6	Rat Level 3 Panel	$15.00
7	Rat Custom Prevalent	$30.00
8	Rat Custom Comprehensive	$39.00
9	Hamster Serology panel	$21.00
10	Gerbil Serology Panel	$21.00
11	Guinea Pig Serology panel	$30.00
12	Rabbit Serology panel	$15.00
13	Mouse Custom Prevalent Profile (PCR)	$225.00
	Idexx-Radil Mouse Prevalent Opti-Q	$199.20
14.	Mouse Custom Comprehensive Profile (PCR)	$326.40
15	Mouse Quarantine PCR Profile	$489.60
16	Mouse Immunocompromised panel	$326.40
17	Rat Custom Prevalent Profile (PCR)	$272.00
18	Rat Custom Comprehensive/Surveillance Profile	$353.60
19	Rat Quarantine PCR Profile	$353.60
20	Rat Immunocompromised panel	$408.00
21	Wild Rodent PCR profile	$163.20
22	Hamster PCR Profile	$163.20
23	Gerbil PCR panel	$190.40
24	Guinea Pig PCR Profile	$217.60
25	Rabbit PCR Profile	$136.00
	Individual Tests:
26	Ind. Serology test added to panel	$3.00
27	Ind. Serology test done alone	$5.00
28	Cost to add PCR test to any panel or Profile (not Helico, mites or pinworms)	$33.50
29	Cost of individual PCR tests done alone (not Helico, mites or pinworms)	$33.50
30	Cost to add Pinworm (parasite) PCR to any std. Panel or Profile	$33.50
31	Cost to add (parasite) fur mites PCR to any std. Panel or profile	$33.50
32	Cost to add both Pinworm and fur mites to panels	$67.00
33	Cost to do both Pinworm and fur mites alone	$67.00
34	Cost for P Pneumotropica (H+J) added to any panel	$33.50
35	Cost for P Pneumotropica (H+J) done alone	$33.50
36	Cost for Helicobacter Panel (H&J) done alone	$33.50
37	Cost for Helicobacter Panel alone	$33.50
38	Cost for Helicobacter Panel added to any panel	$33.50
39	Highest Discount to Standard Contractor Serology and PCR Panels and Profiles or lowest costs per panel or profile (Serology/PCR)
	Bid Component 3
43	Zebrafish Testing PCR	$228.95
44	Highest Discount to Standard Serology and PCR Panels and Profiles or lowest costs per panel or profile (Serology/PCR)	5%
	Bid Component 4
45	Cell line PCR testing – Animal viruses	$185.92
46	Cell line PCR testing – Human viruses	$234.18
47	Cell Line Authentication	$122.31
48	Rodent Genetic Testing	$90.25
49	Highest Discount to Standard Contractor Serology and PCR Panels and Profiles or lowest costs per panel or profile (Serology/PCR)	5%
50	CREDIT of 8% spent toward	$10,898.53

Lowest discounted pricing on Standard Contractor Panels: 20% off July 1, 2013 published Price List. Pricing is available at www.IDEXXBioResearch.com.

MANDATORY SPECIFICATIONS

Program:
I. Contractor Requirements:

1. Free diagnostic supplies, shipping materials and shipping
2. Free rodent sentinels or comparable account credit if sentinels are not available via Contractor.
3. Long term commitment to pricing (at least 1 year) and at least 3 mo. notification of plan to increase prices.
4. Provision and maintenance of quality testing services and quality control with defined retesting (free) for equivocal results at a lab of our choice.
5. Free consultation with laboratory personnel.
6. No additional diagnostic tests added to any custom testing or standard panels without advance notice and permission of UW Director of RARC Pathology and Lab Services or UW-Madison Chief Veterinarian.
7. Free Transfer and access to previously generated UW laboratory data from existing databases to the new secure Contractor maintained on line database with free assistance in training personnel on its use.
8. Free rush testing and over night shipping or replacement of short-dated supplies if needed
9. Technical support (in person) during business hours (7 AM-5 PM M-F CST) for shipping or collection concerns
10. Information Technology (IT) support during normal business hours (see above) for any concerns with database access, testing orders, or any other issues arising from Contractor’s website and database. In addition modifications made if requested to database to provide further clarification and ease of use to reports. Example: UW requests that year long summaries be able to be downloaded as a pdf formatted for 8.5x11 paper and that summary reports contain numbers of animals per total i.e. 3/5 that were positive each quarter (or testing period) for every listed infectious organism.
11. Continuing assistance in educating campus personnel on animal disease and technology issues, database adaption and flexibility, and ongoing research efforts for improvement of testing and technology.
12. Free consultation services with Contractor supplied experts in molecular diagnostics and for interpretation of findings from animal health testing.
13. Reports that print out in a clear format on 8.5x11 paper with all positive test results highlighted in such a manner as to be immediately obvious and all identification numbers of animals and names of all individual profiles, panels and tests be identified clearly on all pages of the report.
14. Online and print resources for vets and investigators for continuing education into animal diseases and their consequences.
15. The science and technology supporting the providing Contractor must match or exceed the highest industry standards for this type of testing.

II. Database detailed Requirements:
1. Web based w/ password
2. Access to old data with timely, no-cost importation into new system (approximately 3 months after award of contract) Winning bid proposer must coordinate with current Contractor(s) to acquire existing data for merger into a new system.
3. Searchable fields – Date, Building, Room, Individual tests and panels (with positives highlighted in some manner), species, strain, sex, age, Investigator(s)and imported in-house data:
i. Ability to find an animal by investigator or submitters’ name, even if there are multiple names in a room
ii.Ability to link health status of colony when animals/investigators change rooms or buildings. Including splitting out the health status based on individual tests/animals/or searchable field groups.
iii. Ability to input information (pathology, parasitology, bacteriology, etc.) obtained on necropsy evaluations (from this campus and affiliates) of sentinels into database (Identifying it as from this or any other institution)

Examples (suggestions for alternative set up welcomed):
Pathology: Normal Abnormal Findings
Parasitology: Negative Positive Findings
(Findings should have expandable space)

4. Information from Contractors database (including data uploaded from UW or other Contractor(s)) must be able to be retrieved into clearly understood and easily configurable health reports, transfer forms, other pdf templates, etc.
5. Contractor upgrades to database are free of charge.
6. Designated individuals at the UW will have administrative control over whoever at the UW and elsewhere can view health reports based on parameters in the searchable fields (e.g. Building, Investigator), and who can request testing or supplies. Examples Dir. Comp. Path lab and SMPH Senior Attending Vet

III. Serology/PCR The panels of tests listed below are custom designed for the UW campus through evaluation of present needs.

A. General specifications

1. Can submit from separate sites with paperwork, collection and shipping supplies and shipping documents supplied for that collection site and separate shipping labels - all results, however to be input into common database
2. Free standard and rush supplies and shipping (overnight if needed)

B. Serology

Bid1 Component
1.Rodent (Required)
a. Parvo panels for mice
MVM
MPV
NS-1

b. Mouse Level 3 panel
EDIM
MHV
MVM
MPV
NS-1

c. Mouse Custom Prevalent
EDIM-rotavirus
MHV
MVM
MPV
NS-1
MNV
TMEV

d. Mouse Custom Comprehensive
EDIM-rotavirus
MHV
MVM
MPV
NS-1
MNV
TMEV
Sendai
LCMV
PVM
Reovirus
Ectromelia
Polyoma

RATS
e. Rat Level 3 Panel
RPV
H-1
NS-1
KRV
RMV
Generic NS-1
SDAV

f. Parvo Panel for Rats
RPV
H-1
RMV
NS-1 (generic parvovirus)
KRV

g. Rat Custom Prevalent
RPV
H-1
KRV
RMV
Generic NS-1
SDAV
RTV
RRV (Pneumocystis)
CARB
IDIR – rotavirus
M.pulmonis

h. Rat Custom Comprehensive
RPV
H-1
KRV
RMV
Generic NS-1
SDAV
RTV
RRV (Pneumocystis)
M. pulmonis
CARB
IDIR - rotovirus
REO
PVM
LCMV

2a. Hamster (Required panel though tests may vary)
SEND
SV-5
PVM
REO
LCMV
E.cun
Cl.piliforme

2b. Gerbil (Required panel though tests may vary)
LCMV
C.pilif
MHV
REO
ROTA
PVM
MVM

3.Guinea Pig    (Required panel though tests may vary)
SEND
SV-5 or P12
PVM
REO
PIV-3
GAV
GPCMV
LCMV
E.Cun
Cl. piliforme

4.Rabbit           (Required panel though tests may vary)
Rota
E. cun
Cl. piliforme
Treponema
CARB

5. Discounted costs for individual serology tests added to panels*
6. No cost substitution of serology tests in panels
7. Discounted costs for individual serology tests alone*

List of serological tests that should be available for Mice, Rats, and other rodents and rabbits

EDIM-rotavirus
MHV
MVM
MPV
NS-1
MNV
TMEV
MTV
Sendai
LCMV
PVM
Reovirus 3
Ectromelia
Polyoma
CARB
Cl. Piliforme
Encephalitazoon cuniculi
Mycoplasma pulmonis
Treponema paraluiscuiculi
Pneumocystis carinii
GPCMV
H-1, RPV, RMV, KRV
Hantaan virus
IDIR
K virus

LDEV
MAD 1&2
MCMV
P13
SDAV/RCV
ROTA (Rb)
SV-5 or P12

C. PCR - Molecular Profiles
   1. Mouse
Custom profiles
a. Custom Prevalent Profile (PCR)
Pinworms
Fur mites
MHV
MPV, HS-1, MVM
MNV
Helicobacter (H. hepaticus, bilis, rodentium, trogontum, typhionius, speies and ganmani as appropriate to species)
TMEV
EDIM/MRV
P. Pneumotropica          (Heyl&Jawetz)

b. Custom Comprehensive Profile (PCR)
Pinworms
Fur mites
MHV
MPV, MVM, NS-1
MNV
TMEV
MRV/EDIM
Helicobacter (H. hepaticus, bilis, rodentium, trogontum, typhionius, speies and ganmani as appropriate to species)
P. pneumotropica (Heyl&Jawetz)
Pneumocystis
Cl. Piliforme
Citrobacter rodentium

c. Quarantine profiles (PCR)
Mouse (not foreign import)
MHV
MNV
Parvo tests (all mouse)
TMEV
EDIM
Rotavirus
Sendai
PVM
Reovirus
LCMV
MAV
Polyoma
PVM
Ectromelia
Helicobacter (genus, H. hepaticus, H. bilis, H. typhlonius, H. rodentium, H. ganmani, H. mastomyrinus [mouse only], H. trogontum [rat only])
Mites and pinworms - Fur mites (Myobia, Myocoptes, Radfordia)
Pinworm (Aspiculuris and Syphacia)

d. Immunocompromised mouse panel, etc. PCR
Pneumocystis
C. bovis
MHV
LCMV
MNV
Parvo: NS-1, MVM, MPV
EDIM
P. pneumotropica
Pseudomonas aeruginosa
Mites and Pinworms

2. RAT
                        Custom profiles
a. Custom Prevalent Profile (PCR)

RCV/SDAV
RPV
KRV
H-1
RMV
RTV
RRV (Pneumocystis)
Helicobacter (H. hepaticus, bilis, rodentium, trogontum, typhionius, speies and ganmani as appropriate to species)
Pinworms
Fur mites

b. Custom Comprehensive/Surveillance Profile
RCV/SDAV
RPV
KRV
H-1
RMV
RTV
Helicobacter (H. hepaticus, bilis, rodentium, trogontum, typhionius, speies and ganmani as appropriate to species)
Pinworms
Fur mites
RRV (Pneumocystis)
CARB
IDIR
M. pulmonis

c. Immunocompromised Rat Panel, etc. PCR
Pneumocystis RRV
C. bovis
SDAV
Parvo: H-1, RVM, RPV, KRV
IDIR
P. pneumotropica
Pseudomonas aeruginosa
Helicobacter sp.
Cl. Piliforme
Streptobacillus moniliformis
Mites and Pinworms

d. Quarantine profiles (PCR)
Rat (not foreign import) PCR
M. pulmonis
CAR bacillus
EDIR
Rat corona virus/SDAV
Rat parvoviruses (H-1, RPV, RMV, KRV)
Pneumocystis carinii/RRV
Pinworms and fur mites
Helicobacter
Streptobacillus moniliformis

3a. Hamster
SV-5 or P12
SEND
PVM
LCMV
ECUN
REO

3b. Gerbil
LCMV
C.pilif
MHV
REO
ROTA
PVM
MVM

4.Guinea Pig
SEND
SV-5 or P12
PVM
REO
PI-3
GAV
GPCMV
E. Cun

5.Rabbit
Rota
E. cun
Pasteurella
Cl. piliforme
Treponema

6. Rodent Wildlife PCR

a. Corona virus

b. Hantaan virus

c. Parvo

d. TMEV

e. .LCMC

f. Helicobacter (H. hepaticus, bilis, rodentium, trogontum, typhionius, speies and ganmani as appropriate to species)

7. Individual PCR tests to be available **
EDIM-rotavirus
MHV
MVM
MPV
NS-1
MNV
TMEV
MTV
Sendai
LCMV
PVM
Reovirus 3
Ectromelia
Polyoma
CARB
Cl. Piliforme
Encephalitazoon cuniculi
Mycoplasma pulmonis
Treponema paraluiscuiculi
Pneumocystis carinii
GPCMV
H-1, RPV, RMV, KRV
Hantaan virus
IDIR
K virus
LDEV
MAD 1&2
MCMV
P13
SDAV/RCV
ROTA (Rb)
SV-5 or P12
And all other bacteria that are commonly found in lab animals for which major labs in industry
will have PCR for.

Bid Component 2

1. Zebrafish/Aquatics testing PCR (Contractor capabilities should be able to accommodate testing for additional organisms as aquatic disease-surveillance programs are further developed)

A. Input our necropsy, parasite and bact data.

B. Organisms to test

(Lab designed panel may be substituted if includes these organisms)
a. Pseudoloma neurophilia
b. Pseudocapillaria sp.(Ex marinum, chelonae, haemophilum)
c.   Mycobacteria sp
d. Piscinoodinium pillare
e . Ichthyophthirius multifiliis
f. Edwardsiella ictaluri

C. Other tests available
a. Pleistophora hyphessobryconis
b.. Infectious spleen and kidney nectrosis

Bid Component 3

1. Primate Serology
SIV, SRV, STLV, HBV, MV

2. Primate PCR Basic Panel
SIV, SRV, STLV, HBV, MV

Bid Component 4
Cell Testing (Required)

Detection of the presence of rodent pathogens (Discounted tests done)

Detection of human pathogens of serious concern to laboratory personnel (Discounted tests done)

Authentication and comparison of cell lines against published profiles (Discounted tests done)

Bid Component 6
1. Genetic Testing Services (Optional) Short panel for genetic contamination testing

Revision History

Materials Distribution Services

ANIMAL HEALTH MONITORING SERVICES