Check the "Contract Updates for the Week"

Click here for piggybacking data form

IN VIVO DRUG DISCOVERY PHARMACOLOGY ASSAYS: PHARMACOKINETICS AND DOSE TOLERABILITY IN RODENTS

(contract last updated 1/20/2017)

SCOPE: Contract for the purchase of In Vivo Drug Discovery Pharmacology Assays: Pharmacokinetics and Dose Tolerability in Rodents.


CONTRACT # DESCRIPTION
17-5725-R1 IN VIVO DRUG DISCOVERY PHARMACOLOGY ASSAYS: PHARMACOKINETICS AND DOSE TOLERABILITY IN RODENTS
CONTRACT ORIGIN: ADDITIONAL INFORMATION:
UW-Madison
Purchasing Services
21 N Park St, Ste 6101
Madison, WI 53715-1218
UW-Madison users contact:
Janet Bresnahan
(608) 262-6335 FAX (608) 262-4467
janet.bresnahan@wisc.edu
  Non-UW-Madison users contact: Vendor Representative
COOPERATIVE PURCHASING:

YES

CONTRACT TERM: October 1, 2016 through September 30, 2017, with automatic renewal extensions to September 30, 2019, unless amended, cancelled or rebid.

Vendor(s)
143309
Sanford Burnham Prebys Medical Discovery Institute
6400 Sanger Rd
Orlando, FL 32827
     
Sales Representative: PHONE # FAX #
David Terry 407-745-2586 407-745-2001
E-mail: dterry@sbpdiscovery.org
  PHONE # FAX #
Ordering/Expediting: 407-745-2586 407-745-2001
Invoice Information: 407-745-2088 407-745-2001
Returns: 407-745-2586 407-745-2001
Supplier Diversity Reporting: 407-745-2057 407-745-2001
Website: www.sbpdiscovery.org
Commodity Code

961-48

962-22

992-26

Federal Employee ID # (FEIN) 15-10197108
Terms: N/30
Delivery: 45 days ARO
Invoicing: Invoices shall reflect contract discounts and net prices.
Pricing Information: Contact agent at (608) 262-6335 or janet.bresnahan@wisc.edu for pricing.

Vendor(s)
144148
WuXi Apptec Hong Kong Limited
Unit 10 11/F Block B
New Trade Plaza 6 On Ping St
Shatin, Hong Kong
     
Sales Representative: PHONE # FAX #
Linda Zhao    
E-mail: linda.c.zhao@wuxiapptec.com
  PHONE # FAX #
Ordering/Expediting:    
Invoice Information:    
Returns:    
Supplier Diversity Reporting:    
Website: www.wuxiapptec.com
Commodity Code

961-48

962-22

992-26

Terms: N/30
Delivery: Delivery time depends on specific studies.
Invoicing: Invoices shall reflect contract discounts and net prices.
Pricing Information: Contact agent at (608) 262-6335 or janet.bresnahan@wisc.edu for pricing.

SPECIFICATIONS

 

A. Contractor must be able to provide one or more services similar to those below without necessarily exactly matching the specific parameters suggested below, e.g., time after dosing.

1. Examples of PK study designs of Interest:

    1. Single compound, 1dose, 1 route, 0.5hr and 2hr
    2. Brain tissue penetration study, Single compound, 1dose, 1 route, 0.5hr and 2hr
    3. Single compound, 1dose, 1 or 2 routes, 0.5 h, 2h, 4h, and 7h
    4. Single compound, 1 dose, 2 routes, 0, 0.5, 1, 2, 4, 8, 24 hrs

 

2. Examples of Dose Tolerability Studies of Interest

    1. Single Dose Tolerability (1 day), Five dose levels, 1 route, 7 Blood sampling times up to 24h post dosing per animal
    2. Multi- Dose Tolerability (5 days), Five dose levels, 1 route, Animals receive repeat dose once daily for five days, 7 Blood sampling times up to 24h post dosing per animal

 

B. For all tests bioanalysis must be performed by LC/MS/MS.

 

C. Contractor must address each of the following in the bid response for each test quoted. Attachments requested must be attached to your bid responses.

  1. Specify amount of compound (or a typical range) needed per study
  2. Specify route of administration
  3. Specify number of rodents used per study to permit rigorous evaluation of compounds, minimum = 3
  4. Specify blood sampling times after dosing
  5. Describe content and format of data report (Excel, Word, PDF, etc.) provided at end of study
  6. Provide a mock (but complete) data report for evaluation as an attachment to your bid response
  7. Specify amount of time (or a typical range) from receipt of compounds to sending the final data report.
  8. Specify that a written description of the protocols used for a compound(s), suitable for investigators to use in grant applications or publications, will be available upon request.

Revision History

(1/20/17): updated to show name change FROM: WuXi Apptec TO: WuXi Apptec Hong Kong Limited.
link to top of document